Cloning and Characterization of Rat Spermatid Protein SSP411: A Thioredoxin-Like Protein
نویسندگان
چکیده
منابع مشابه
Cloning, expression and characterization of mouse spermatid specific thioredoxin-1 gene and protein.
Thioredoxins are proteins that participate in different cellular processes via redox-mediated reactions. For humans, we have recently described two novel members of this family that display a male germ cell specific expression pattern, named spermatid specific thioredoxin (Sptrx-1 and Sptrx-2 respectively). We report here the cloning and characterization of the mouse Sptrx-1 gene and protein, w...
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Following elongation of spermatids in mammals, the histones are replaced by a set of basic nuclear transition proteins; in the rat there are four, named TP1-TP4. Of these, TP1 and TP2 are well characterized. Here we report the purification to homogeneity of TP4 from rat spermatids. It is a low molecular mass (about 13-20 kDa) basic protein with arginine and lysine constituting 24 mol % and hist...
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متن کاملHuman spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity.
Spermatid-specific thioredoxin-1 (Sptrx-1) is the first member of the thioredoxin family of proteins with a tissue-specific expression pattern, found exclusively in the tail of elongating spermatids and spermatozoa. We describe here further biochemical characterization of human Sptrx-1 protein structure and enzymatic activity. In gel filtration chromatography human Sptrx-1 eluates as a 400 kDa ...
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ژورنال
عنوان ژورنال: Journal of Andrology
سال: 2004
ISSN: 0196-3635
DOI: 10.1002/j.1939-4640.2004.tb02819.x